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>Shipping 84467-54-9 288.26 5 mg; 10 mg; 25 mg > 98 % +4°C wet ice H,N HCI C15H23Cl2N Cl MI8221 N,N-Didesmethylsibutramine-D7 Hydrochloride 84467-54-9 (1) 295.31 2.5 mg; 5 mg; 10 mg > 95 % +4°C wet ice >CAS number >Molecular weight >Size >% purity >Storage temp.

>Shipping HCI C15H 16Cl2ND7 Terfenadine Alcohol > CAS number NDA > Molecular weight 487.67 > Size 10 mg; 25 mg; 50 mg > % purity > 95 % > Storage temp. +4°C > Shipping wet ice MM8184 C32H 41 NO3 Substrates/APIs ref. page Metabolites ref. page Acebutolol NDA - Diacetolol Hydrochloride MM7886 60 Diacetolol-D7 Hydrochloride Ml7887 61 Aceclofenac AP8073 9 Acetaminophen-D3 MI7988 9 Acetaminophen Sulphate Potassium Salt MM7989 52 I D CD AP8074 9 Acyclovir Sodium Salt AP8075 9 Adrafinil AP8076 10 Adrenaline-D3 Hydrochloride [(+/-)epinephrine-D3] MI8050 10 Alprazolam AP8077 10 Hydroxyalprazolam MM7889 63 Alprazolam-D5 Ml7888 10 Hydroxyalprazolam-D5 Ml7890 63 Amiodarone Hydrochloride M02026 11 Mono-N-Desethylamiodarone Hydrochloride (MDEA) MM7892 56 Amiodarone-D4 Hydrochloride MI7891 11 Mono-N-Desethylamiodarone-D4 Hydrochloride (MDEA-D4) ~vl CO CD CO 56 Amlodipine AP8078 11 Amlodipine-D3 MI7974 11 Amlodipine-D4 Besylate Ml7981 11 Anastrozole AP8079 12 Androstane-3a-17P-Diol-D3 MI8248 12 Androstane-3a,17P-Diol-3-O-P-D-Glucuronide-D3 MI8239 52 Androstane-3a,17P-Diol-17-O-P-D-Glucuronide MM8235 53 Androstane-3 |3-17|3-Diol-D3 MI8250 12 Androstane 3|3,17|3-Diol-3-O-|3-D-Glucuronide-D3 MI8240 52 Androstane-3-P,17-P-Diol-17-O-P-D-Glucuronide MM8236 53 Androsterone NDA Androsterone Glucuronide MM8234 53 Androsterone-D5 MI8247 12 Androsterone Glucuronide-D4 MI8238 53 Androsterone Glucuronide-D5 MI8242 53 Epi Androsterone-D5 MI8237 12 Epi Androsterone-P-Glucuronide MM8249 54 Aripiprazole AP8080 13 Aripiprazole-D8 Ml7894 13 Artemether-D3 MI8203 13 Atazanavir AP8081 13 Atorvastatin Calcium Salt AP8082 14 Benazepril Hydrochloride AP8083 14 Bezafibrate AP8084 14 Bufuralol M02027 14 1',2'-Dihydroxybufuralol M02038 61 Bufuralol-D9 Hydrochloride MI8034 14 1',2'-Dihydroxybufuralol-D9 M02039 62 Bupropion Hydrochloride M02024 15 Hydroxy Bupropion [Mixture of (R,R) and (S,S)] MM8217 64 Dihydrobupropion MM7896 63 Bupropion-Dg Hydrochloride Ml7895 15 Dihydrobupropion-D9 Ml7897 63 1,4 Butanediol Mononitrate-D8 MI8060 15 Capecitabine NDA 5,6-Dihydrofluorouracil MR8035 61 Capecitabine-D8 Ml7986 15 Deoxy-5-Fluorocytidine-D2 (5-DFCR-D2) Ml7900 55 Capecitabine-D11 Ml7898 15 Deoxy-5-Fluorocytidine (5-DFCR) MM7899 55 5-Doxifluridine-D2 no perscription phentermine (5-DFUR-D2) Ml7902 62 Carboplatin AP8086 16 Carprofen AP8087 16 Carvedilol AP8088 16 Metabolite M8 of Carvedilol MM8019 71 Carvedilol-D5 MI7993 16 Metabolite M8 of Carvedilol-D5 MI8044 71 Catharanthine AP8089 16 Ceftiofur-D3 Ml7903 17 Celecoxib NDA Celecoxib Carboxylic Acid MM8191 54 Hydroxycelecoxib MM8192 64 Cetirizine Dihydrochloride AP8090 17 Chlorzoxazone M02017 18 6-Hydroxychlorzoxazone M02003 64 Chlorzoxazone N-Glucuronide M02048 54 Cholesterol NDA 4-a-Hydroxycholesterol MM8189 64 4-P-Hydroxycholesterol MM8190 65 4-P, 7-a-Dihydroxycholesterol MM8233 64 Ciprofloxacin Hydrochloride AP8091 18 Clonazepam AP8092 19 7-Aminoclonazepam MM7905 52 Clonazepam-D4 Ml7904 19 7-Aminoclonazepam-D4 Ml7906 52 Clopidogrel Hydrogen Sulfate AP8093 19 Clopidogrel Carboxylic Acid MM7908 54 Clopidogrel-D3 Hydrogen Sulfate Ml7907 19 Clozapine AP8094 19 Desmethylclozapine MM7910 56 Clozapine-D3 Ml7909 20 Codeine-D3 MI8051 20 7-Hydroxycoumarin NDA 7-Hydroxycoumarin-O-P-D-Glucuronide M02047 65 Cyproterone Acetate AP8095 20 Darifenacin Hydrobromide AP8096 20 Deltamethrin-D5-13C (M+6) MI8045 20 Desipramine NDA 2-Hydroxydesipramine Hydrochloride MM7914 65 2-Hydroxydesipramine-D6 Hydrochloride Ml7915 65 3,4-Diaminopyridine-D3 Ml7987 21 Diazepam-D5 Ml7911 21 Nordiazepam-D5 | Ml7925 72 Diclofenac Sodium Salt M02018 22 4'-Hydroxydiclofenac M02004 65 Diclofenac Acyl-D-Glucuronide MM8081 61 Diclofenac-D4 MI7995 22 4'-Hydroxydiclofenac-D4 M02041 66 Didanosine AP8098 22 N,N-Diethyltoluamide-D10 MI8068 22 Digoxin-D3 Ml7956 23 Dihydroergotamine Methanesulfonate AP8099 23 Diltiazem NDA Deacetyldiltiazem MM7969 54 N-Desmethyldiltiazem MM7970 56 Diltiazem-D4 Ml7971 23 Deacetyldiltiazem-D4 Ml7973 55 N-Desmethyldiltiazem-D4 Ml7972 57 Docetaxel AP8100 23 Dolasetron Mesylate Monohydrate AP8101 24 Hydrodolasetron MM7912 63 Donepezil Hydrochloride AP8102 24 Donepezil-D7 Ml7913 24 Dutasteride AP8104 24 Efavirenz 13C6 MI8014 24 Ellagic Acid NDA 3,3'-Di-O-Methylellagic Acid MR7960 60 4,4'-Di-O-Methylellagic Acid MR7959 60 Emtricitabine AP8105 25 Entacapone AP8106 25 Entacapone-D10 (E isomer) Ml7982 25 Ethynyl Estradiol M+6 MI8230 25 Exemestane NDA 17-P Hydroxyexemestane MM7962 66 Famciclovir AP8107 26 Felodipine AP8108 26 Felodipine-D3 Ml7975 26 Fipronil AP8110 26 Florfenicol AP8111 26 Florfenicolamine Hydrochloride MM7980 62 Floxuridine AP8112 27 Fluconazole AP8113 27 Flumequine AP8114 27 7-Hydroxyflumequine MM7965 66 Flurazepam NDA Desalkyflurazepam MM8097 55 Gemcitabine Hydrochloride AP8115 27 Homo-Tienilic Alcohol M02002 27 HRP 2000 (VA-2914)-D3 MI8055 28 Mono-Desmethyl HRP 2000 (VA-3877)-D3 MI8056 57 Hydrochlorothiazide AP8116 28 Hydrochlorothiazide-D2,15N2 Ml7916 28 Imazalil AP8117 28 Imidapril AP8118 28 Indobufen AP8119 29 Ioversol AP8120 29 Irbesartan AP8121 29 Isosorbide Nitrate AP8122 29 Ketamine NDA (R)-Norketamine Hydrochloride MM8027 72 (R,S)-Norketamine Hydrochloride MM8025 72 Ketamine-D6 Hydrochloride Ml8012 29 (R,S)-Norketamine-D6 Hydrochloride MI8028 72 (S)-Norketamine Hydrochloride MM8026 73 (S)-Norketamine-D6 Hydrochloride MI8036 73 Ketoconazole AP8123 30 Deacylketoconazole MM7979 55 Ketoconazole-D3 MI7978 30 Ketoprofen AP8124 30 Ketoprofen-D3 MI8003 30 Kynuramine, 2HBr MM8211 30 Kynuramine-13C, D2, 2HBr MI8212 31 Kresoxim-Methyl (Z)-Isomer; [methyl (E)-methoxyimino- [a-(o-tolyloxy)-o-tolyl]acetate (Z)-Isomer] MR8229 31 (R-S)-Lercanidipine Hydrochloride AP8125 31 (S)-Lercanidipine Hydrochloride MR8038 31 (R)-Lercanidipine Hydrochloride MR8039 31 (R,S)-Lercanidipine-D3 Hydrochloride Ml7961 32 (S)-Lercanidipine-D3 Hydrochloride MI8040 32 _eurosine AP8126 32 _osartan NDA _osartan Acid Metabolite (EXP3174)hydrocodone online prescription qoclick MM7918 70 _osartan-D9 Ml7917 32 _osartan-D9 Acid Metabolite (EXP3174-D9) Ml7919 70 _umefantrine NDA Desbutyl-_umefantrine-D9 MI8200 70 Melatonine AP8130 32 S-Mephenytoin M02028 33 Mequitazine-D2 Hydrochloride MI8182 33 Metformine-D6 MI8210 33 Methotrexate AP8131 33 3-Methoxymorphinan Hydrochloride MM8206 33 Dextromethorphan NDA 3-Methoxymorphinan-D3 Hydrochloride MI8207 71 Metronidazole-D4 Ml7922 34 Hydroxymetronidazole-D4 MI7924 66 Midazolam M02022 34 1'-Hydroxymidazolam M02040 66 1'-Hydroxymidazolam-O-|3-D-Glucuronide M02044 67 Mifepristone (RU42848) AP8132 34 N-Desmethylmifepristone MM7921 57 Didesmethylmifepristone (RU42848) MM8043 61 Hydroxymifepristone (RU42698) MM8020 67 Mifepristone-D3 Ml7920 34 N-Desmethylmifepristone-D3 MI8042 57 Hydroxymifepristone-D3 (RU42698-D3) MI8022 67 Mosapride AP8133 34 Naringenin NDA Naringenin-4'-O-|3-D-Glucuronide M02045 71 Naringenin-7-O-P-D-Glucuronide M02046 72 Navelbine Ditartrate AP8134 35 Nifedipine AP8135 35 Nifedipine-D3 Ml7976 35 N iflum icAci d NDA 5-Hydroxyn iflum icAci d MM8031 67 Nisoldipine-D3 MI7977 35 Nisoldipine-D4 MI8188 35 Nomegestrol Acetate-D3 MI8201 36 p-N-Nonylphenol (RING-13C6) MI8228 36 Noradrenaline-D6 Hydrochloride MI8232 36 D_-3,4-Dihydroxyphenyl Glycol-D213C MI7983 62 MHPG Sulfate-D3 Potassium Salt MI8013 73 Olanzapine AP8136 36 Desmethylolanzapine MM7927 57 Olanzapine-D3 Ml7926 36 Olmesartan Medoxomil AP8137 37 Omeprazole AP8138 37 Omeprazole Sulfone MM8018 74 Omeprazole 5-Carboxylic Acid MM7935 74 5-Hydroxyomeprazole Sulfide MM7931 68 Omeprazole Sulfide 5-Carboxylic Acid MM7934 73 5-Hydroxyomeprazole MM7932 68 5-Hydroxyomeprazole Sulfone MM7933 68 Omeprazole-D3 MI8015 37 Omeprazole-D3 Sulfide MI8016 74 Omeprazole-D3 Sulfone MI8017 74 5-Hydroxyomeprazole-D3 MI8213 68 Ondansetron Hydrochloride AP8139 37 _-Ornithine-13C Hydrochloride Ml7963 37 _-Ornithine-13C D2 Hydrochloride Ml7964 38 Oseltamivir Acid Hydrochloride MM8202 38 Oxybutynin Hydrochloride NDA 38 N-Desethyloxybutynin Hydrochloride MM7937 56 Oxybutynin-D10 Hydrochloride Ml7936 38 Oxycodone Hydrochloride NDA Noroxycodone Hydrochloride (N-desmethyloxycodone) MM8024 73 Oxycodone-D3 Hydrochloride MI8023 38 Paclitaxel AP8183 38 6a-Hydroxypaclitaxel M02006 68 Pantoprazole Sodium Salt AP8140 39 Pentoxifylline NDA - Pentoxifylline Acid Metabolite (1-(4-carboxybutyl)-3,7-dimethyl-xanthine) MM7939 74 Pentoxifylline Alcohol Metabolite (1-(5-hydroxyhexyl)-3,7-dimethyl-xanthine) MM7938 75 Pentoxifyl li ne-D6 NDA - Pentoxifylline-D6 Acid Metabolite Ml7940 75 Phloroglucinol NDA Phloroglucinol-13C6 MI8180 39 Phloroglucinol-1-P-O-Glucuronide MM8227 75 Pimobendane NDA O-Desmethyl-Pimobendan (UD-CG 212) MM8205 75 Pioglitazone Hydrochloride AP8141 39 Pirenoxine AP8142 39 Pravastatin Sodium Salt AP8143 39 Propranolol Hydrochloride M02029 40 5-Hydroxypropranolol M02015 69 Propranolol-D7 MI8072 40 5-Hydroxypropranolol-D7 M02042 69 Pyriproxyfen-D6 MI8231 40 Quetiapine Fumarate AP8144 40 Quetiapine-D4 Hemifumarate Ml7941 40 Ramipril AP8145 41 Ramipril Acyl-D-Glucuronide MM8080 75 Ramipril Diketopiperazine (EP impurity D) MR8071 76 Ramiprilat MM8070 76 Ranitidine Hydrochloride AP8146 41 Rebamipide AP8147 41 Resveratrol AP8029 41 Resveratrol 3-O-D-Glucoside (piceid) M02035 76 Resveratrol 3-O-D-Glucuronide M02036 76 Resveratrol 4'-O-D-Glucuronide M02037 77 Resveratrol-3-O-Sulfate MM8199 77 Resveratrol-3-O-D-Glucuronide D4 MI8218 76 Resveratrol-4'-O-D-Glucuronide Minimum D4 MI8219 77 Resveratrol-3-O-Sulfate Minimum D4 MI8220 77 Rifapentine AP8149 41 Rilmenidine Phosphate AP8150 42 Rilmenidine-D4 Ml7967 42 Risedronate Sodium Salt AP8148 42 Risedronate-D413C (M+5) Sodium Salt MI8061 42 Risperidone AP8151 42 9-Hydroxyrisperidone MM7943 69 Risperidone-D5 Ml7942 43 9-Hydroxyrisperidone-D4 Ml7944 69 Ropinirole Hydrochloride NDA Despropylropinirole Hydrochloride MM7946 60 Ropinirole-D7 Hydrochloride Ml7945 43 Rosiglitazone Maleate AP8152 43 N-desmethylrosiglitazone MM8033 58 Rosiglitazone-D5 Maleate Ml7947 43 Sarafloxacin AP8153 43 Sertraline Hydrochloride AP8154 44 Sibutramine NDA N,hydrocodone online prescription qoclick N-Didesmethylsibutramine Hydrochloride MM8225 77 N-Monodesmethylsibutramine Hydrochloride MM8223 58 Sibutramine-D6 Hydrochloride MI8224 44 N-N-Didesmethylsibutramine-D7 Hydrochloride MI8221 78 N-Monodesmethylsibutramine-D7 Hydrochloride MI8222 58 Sildenafil Citrate AP8155 44 Desmethylsildenafil Citrate MM7949 58 Sildenafil-D8 Citrate Ml7948 44 Desmethylsildenafil-D8 Citrate Ml7950 58 Sulbactam-D2 Sodium Salt MI8216 44 Sumatriptan Succinate AP8157 45 Tabersonine AP8158 45 Tadalafil AP8159 45 Tamoxifen Citrate AP8160 45 Temozolomide AP8161 45 Tenatoprazole AP8162 46 Terbinafine Hydrochloride AP8163 46 Terfenadine M02023 46 Terfenadine Alcohol MM8184 78 Fexofenadine Hydrochloride AP8109 62 Testosterone M02021 46 11 a-Hydroxytestosterone M02007 69 6 P-Hyd roxytestosterone M02008 70 Tetrazepam AP8164 46 Tilmicosin AP8165 47 Tolbutamide M02020 47 4-Hydroxytolbutamide M02009 70 Trilostane AP8166 47 Trimebutine Maleate NDA N-Desmethyltrimebutine Hydrochloride MM7951 59 O-Desmethyltrimebutine Hydrochloride MM7952 59 N-Desmethyl-O-Desmethyltrimebutine MM7953 59 Trimebutine-D3 Maleate Ml7957 47 N-Desmethyltrimebutine-D3 Hydrochloride Ml7958 59 1,3,5-Trimethoxybenzene-13C6 MI8181 48 Tropisetron Hydrochloride AP8167 48 Tulobuterol Hydrochloride AP8168 48 Valsartan AP8169 48 Valsartan-D9 Ml7954 48 Vardenafil AP8171 49 Verapamil Hydrochloride AP8170 49 Vinblastine Sulfate AP8172 49 Vincristine Sulfate AP8173 49 Vindoline AP8174 49 Ziprasidone AP8175 50 Ziprasidone-D8 Ml7955 50 Zolm itri ptan AP8176 50 N-Desmethylzolmitriptan Hydrochloride MM8058 59 Zolmitriptan-D6 MI8057 50 N-Desmethylzolmitriptan-D3 Hydrochloride MI8059 60 Zolpidem AP8177 50 Zolpidem-D6 Ml7968 51 Zopiclone AP8178 51 NDA: no data available * Contact us for further information Chemical substrates & their metabolites for in vitro experiments CYP Chemical substrates Metabolites 1A1 7-Ethoxyresorufin Resorufin 1A2 Phenacetin1 O-desethyl phenacetin (acetaminophen) 7-Ethoxyresorufin2 Resorufin Caffeine2 Paraxanthine (3-N-desmethylcaffeine) Theophylline2 N-Desmethyltheophylline Tacrine2 1-Hydroxy tacrine Clozapine N-Desmethylclozapine Olanzapine N-Desmethylolanzapine Propranolol N-Deisopropyl Propranolol Ropinirole N-Despropyl Ropinirole 1B1 7-Ethoxyresorufin Resorufin Estradiol 4-Hydroxy Estradiol 2A6 Coumarin1 7-Hydroxycoumarin Nicotine1 Cotinine (5'-cetonicotine) 7-Ethoxycoumarin 7-Hydroxycoumarin 2B6 Bupropion1 R,R- and S,S-Hydroxybupropion Efavirenz1 Hydroxy Efavirenz Propofol2 Hydroxy Propofol S-Mephenytoin2 Nirvanol (N-desmethyl S-Mephenytoin) 2C8 Paclitaxel1 6a-Hydroxy Paclitaxel Rosiglitazone2 Para Hydroxy Rosiglitazone Amodiaquine2 N-Desethylamodiaquine Amiodarone N-Desethyl Amiodarone (MDEA) 2C9 Diclofenac1 4'-Hydroxy Diclofenac S-warfarin1 7-Hydroxy S-Warfarin Tolbutamide1 4-Hydroxytolbutamide Flurbiprofen2 4'-Hydroxyflurbiprofen Phenytoin2 4'-Hydroxyphenytoin S-Mephenytoin2 Nirvanol (N-desmethyl S-mephenytoin) Irbesartan Monohydroxylated Irbesartan Derivatives Losartan EXP3174 (5-carboxy iosartan) 2C18 Homo-Tienilic Alcohol (3-[2,3-dichloro-4-(thiophene-2- 5-Hydroxy Homotienilic Alcohol carbonyl)phenoxy]hydroxypropyl ether) (1)Preferred substrate (from FDA guidance 2006) (2)Acceptable substrate (from FDA guidance 2006) Chemical substrates & their metabolites for in vitro experiments CYP Chemical substrates 2C19 S-Mephenytoin1 Fluoxetine2 Omeprazole2 Diazepam Imipramine 2D6 Bufuralol1 Dextromethorphan1 Debrisoquine2 Desipramine Imipramine Propranolol Risperidone 2E1 Chlorzoxazone1 7-Ethoxycoumarin p-Nitrophenol 3A4/5 Midazolam1 Testosterone1 Dextromethorphan2 Erythromycin2 Nifedipine2 Terfenadine2 Triazolam2 Alprazolam Amiodarone Diazepam Diclofenac Dihydroquinidine Dihydroquinine Quinine Quinidine Sildenafil (1)Preferred substrate (from FDA guidance 2006) (2)Acceptable substrate (from FDA guidance 2006) hydrocodone online prescription qoclick Metabolites 4'-Hydroxy S-Mephenytoin 0- Dealkyl Fluoxetine 3- Hydroxy Omeprazole Nordiazepam N-Desmethyl Imipramine 1- Hydroxy Bufuralol Dextrorphan (O-desmethyl dextromethorphan) 4-and 7-Hydroxy Debrisoquine 2- Hydroxy Desipramine 2-Hydroxy Imipramine 4- and 5-Hydroxy Propranolol 9-Hydroxy Risperidone 6- Hydroxy Chlorzoxazone 7- Hydroxycoumarin p-Nitrocatechol 1'- and 4-Hydroxy Midazolam 6p-Hydroxytestosterone Dextrorphan N-Desmethyl Dextromethorphan N-Desmethyl Erythromycin Dehydronifedipine Terfenadine Alcohol 4-Hydroxy Triazolam 4- Hydroxy hydrocodone online prescription qoclick Alprazolam N-Desethyl Amiodarone (MDEA) Nordiazepam (N-desmethyl diazepam) 5- Hydroxy and 4',5-Dihydroxydiclofenac 3S-Hydroxy Dihydroquinidine 3S-Hydroxy Dihydroquinine 3S-Hydroxy Quinine 3S-Hydroxy Quinidine N-Desmethylsildenafil Technical documentation available upon request or at www.bertinpharma.com • Products are for research use only Tel: +33 139 306 036 • Fax: +33 139 306 299 • bioreagent@bertinpharma.com See below our 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