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Indian CRAMS sector The opportunity for CRAMS in India is large. US companies have reduced their R&D spending in the recent past. These companies are outsourcing their R&D to reduce their operating expenses and hence, shift base to low-cost destinations, possessing high chemistry skills, making India and China preferred outsourcing destinations. The Indian pharmaceutical outsourcing providers possess capabilities to provide late stage discovery (research chemistry) and drug development services.

However, they are in the process of building research biology skills to facilitate early stage discovery. The Indian contract research industry grew at a 65% CAGR (2007-10) to reach around US$ 1.5 billion in 2010, outpacing the 15% growth in the global contract research market over the same period (the global market stood at US$ 25 billion in 2010). Contract manufacturing operations are the largest contributors (more than 60%) to the total CRAMS earnings.

India has emerged as a master in value engineering products, which are similar to patented products in a non-infringing manner, strengthening its expertise to challenge patents in the US FDA, which was perceived as a threat to global companies.

However, the Indian buy hydrocodone with free Patent Protection Amendment Act, 2005 addressed these threats and opened larger opportunities for contract research operations from regulated markets. Credible estimates suggest that the Indian CRAMS space is expected to grow at 15% over the medium term.

India, an enabler for contract research outsourcing Potential savings in outsourcing end-to-end research and development to India 120 100 80 60 40 20 0. 8.9 20-25 Potential cost saving of ~ 60% 25 35-40 : '' Total R&D cost in India Total R&D Cost in US Research biology Research chemistry Development cost Source: ICRA report (June 2011) Pillars of business sustainability Integrated operations Orchid commenced xanax sleepiness its operations in 1994, and is one of the few, fully-integrated, globally-present Indian buy hydrocodone with free pharmaceutical companies. Orchid's state-of-the-art R&D and manufacturing infrastructure received approvals from global regulatory authorities and enjoys marketing alliances with large globe generic majors, buy hydrocodone with free distributors and agencies. Multi-horizon strategy Orchid's multi-tier apap and hydrocodone integration captures every dimension of the pharmaceutical value chain. •Segments: Active Pharmaceutical Ingredients (APIs) to Finished Dosage Forms (FDFs) •Products: Multi-therapeutic •Markets: Regulated and Emerging •Value chain: Drug discovery to delivery •New Drug Discovery •Novel Drug Delivery •CRAMS •For in-house generics •For regulated markets •For emerging markets •Generics for regulated markets •Branded for emerging markets •Branded for India Pillars of business sustainability Manufacturing operations API operations: Orchid has three API manufacturing sites - two in India (Chennai and Aurangabad) and one in China (joint venture).

The API manufacturing complex located at Alathur, Chennai, buy hydrocodone with free is among do generic xanax look the largest integrated antibiotic manufacturing facilities in India. It buy hydrocodone with free specialises in the manufacture of cephalosporin APIs (sterile and non-sterile) and is approved by leading global regulatory agencies like the medication online phentermine tramadol US FDA, UK MHRA, PMDA, EDQM, TGA and DMA, in addition to several quality, environmental and safety management recognitions.



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