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SECTION III - INTRODUCTION SUMMARY OF INDUSTRY THE GLOBAL PHARMACEUTICAL INDUSTRY The pharmaceutical industry, which includes the development, production and marketing of pharmaceutical products, is characterized by its large size, growth, globalization and significant investment in research and development. The global pharmaceutical industry is driven by a continuing need for medicines for the treatment of disease, demographic shifts that strengthen this underlying demand and improved healthcare hydrocodone with out prescription infrastructures that are providing people with greater access to medicines. According to IMS, sales in the global pharmaceutical industry exceeded U.S.$845 billion in 2011 with a 7% positive growth rate. The global pharmaceutical industry has historically been dominated by the United States, European and Japanese markets. In 2011, the United States market was the largest market accounting for sales of U.S.$320 billion. (Source: IMS Health - MIDAS dataset September 2011.) However, it is now believed that China, India, Brazil and Russia are very attractive nations for growth in the pharmaceutical industry. These markets offer a high growth potential due to their rising GDPs, expanding access to healthcare, improving intellectual property hydrocodone with out prescription and regulatory environments. THE INDIAN PHARMACEUTICAL INDUSTRY The size of the Indian pharmaceutical industry was estimated at U.S.$29.1 billion (including exports) in 2011-2012. Of this, the domestic formulations market was valued at U.S.$11.6 billion (or ' 556.6 billion). (Source: CRISIL Report - Industry Information - is hydrocodone the same as codeine Industry Overview (February 2013).) Indian pharmaceutical companies have manufacturing opportunities in the following segments - •Domestic formulations market; •Formulations exports; and •Bulk drugs. A brief description of these key segments is set forth below. Domestic Formulations Market The domestic formulations industry is highly fragmented in terms of both, number of manufacturers and variety of products However, organized players dominate the formulations market and the top 10 formulations companies accounted for 41.3% of the total formulations sales. (Source: CRISIL Report - Industry Information-Industry Overview (February 2013).) Domestic demand for formulations grew at a CAGR of 15% during 2006-2007 to 20112012, driven by a rise in consumption of drugs treating lifestyle diseases. The domestic formulations market is likely to expand to over ' 1 trillion in 2016-2017, registering a CAGR of 13-15%. (Source: CRISIL Report - Opinion - Manufacturing Opportunities - Manufacturing opportunities for Indian pharma companies to remain upbeat (December 2012).) Formulations Exports Between 2006-2007 and 2011-2012, formulations exports grew strongly at a CAGR of approximately 22%.

During this period, exports fake oxycontin 80 to regulated markets also grew at a robust CAGR of approximately 29% owing to increasing penetration of generics in key markets such as the United States and Europe. (Source: CRISIL Report - Opinion - Manufacturing Opportunities - Manufacturing opportunities for Indian pharma companies to remain upbeat (December 2012).) Exports to semi-regulated markets, which have grown at 16% over the same period, also supported growth in overall exports. (Source: CRISIL Report - Opinion - Formulations Exports - Long term export potential - Double-digit growth in formulations exports to continue (December 2012).) Over the next few years, formulations exports are expected to continue to grow at a CAGR of hydrocodone with out prescription 14-16%, driven by the growing opportunity from off-patent drugs in regulated markets and a favorable growth in semi-regulated markets. (Source: CRISIL Report - Opinion - Manufacturing Opportunities - Manufacturing opportunities for Indian pharma companies to remain upbeat (December 2012).) Bulk Drugs Bulk drug exports too are expected to grow at a similar pace of 14-16% CAGR, as the growing generics market and rising cost pressures faced by innovators provide a significant opportunity. Additionally, India'hydrocodone with out prescription s key strengths such as low-cost manufacturing, high process chemistry skills, manufacturing facilities and increasing number of drug master filings ("DMFs") are expected to drive growth in bulk drug exports.

(Source: CRISIL Report - Opinion - Manufacturing Opportunities - Manufacturing opportunities for Indian pharma companies to remain upbeat (December 2012).) THE INDIAN BIOTECHNOLOGY SECTOR The biotechnology industry in India, comprising approximately 380 companies, has grown threefold in the last five years, to reach U.S.$4 billion in fiscal 2011.



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