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Adding data to the database The database is available to the public via the web-site: do you no were i can find info on oxycontin www.wikipharma.

org and after a simple 3.58 n online pharmacy phentermine login registration, anyone may propose additions to the database contents. All data proposed to be added to the database will have to be approved by the database administrator. The administrator will check whether the proposed additions seem reasonable and compatible with the aims of the database. Data that have either been published in the open scientific literature or that have been sufficiently peer reviewed and made publicly 3.58 n online pharmacy phentermine available by other means, will be included. In a wiki all users and contributors are responsible for quality assurance. For further scrutiny and evaluation of the data, the user is referred to the original source of the data. The goal is for WikiPharma to be an easy accessible, comprehensive, and up-to-date source for information about the environmental toxicity of APIs.

If this goal will be reached is up to the users of the database. References Andreozzi R, Caprio V, Ciniglia C, de Champdore M, Lo Giudice R, Marotta R, Zuccato E. Occurrence in Italian STPs, fate, and preliminary assessment on algal toxicity of amoxicillin. Environmental Science and Technology 38: 6832-6838 Backhaus T, Grimme LH. The toxicity of antibiotic agents to the luminescent bacterium Vibrio fischeri.

Chemosphere 38 (14): 3291-3301 Bellini A, Parolini M, Cogni D, Pedriala A, Provini A. A multi-biomarker assessment of the impact of the antibacterial trimethoprim on the non-target organism Zebra mussel (Dreissena polymorpha). Comparative biochemistry and physiology, part C 150: 329-336 Cooney JD. (Ed.), Fundamentals of Aquatic Toxicology - Effects, Environmental Fate, and Risk Assessment, 3.58 n online pharmacy phentermine second ed.

Desbrow C, Routledge EJ, Brighty GC, Sumpter JP, Waldock MJ. Identifcation of estrogenic chemicals in sewage treatment works effluent. Chemical fractionation and in vitro biological screening. Environmental Science and Technology 32: 1549-1558 European Commission. European Commission Technical Guidance Document in Support of Commission Directive 93/67/EEC on Risk Assessment for New Notified Substances and Commission Regulation (EC), 2003; No 1488/94 on Risk Assessment for Existing Substances, Part II.

http:// ecb.jrc.ec.europa.eu/documents/TECHNICAL_GUIDANCE_DOCUMENT/EDITION_2/ tgdpart2_2ed.pdf EMA, European Medicines Agency. Committee for Medicinal Products for Human Use, Guideline for the environmental risk assessment of medicinal products for human use. Pharmaceuticals in the Environment - Sources, Fate, Effects and Risks, second ed. Lange R, Hutchinson TH, Croudace CP, Siegmund F, Schweinfurth H, Hampe P, Panter GH, Sumpter JP. Effects of the synthetic estrogen 17a-ethinylestradiol on the life-cycle of the fathead minnow (Pimephales promelas).

Environmental Toxicology and Chemistry 20 (6): 1216-1227 Metcalfe CD, Metcalfe TL, Kiparissis Y, Koenig BG, Khan C, Hughes RJ, Croley TR, March RE, Potter T. Estrogenic potency of chemicals detected in sewage treatment plant effluents as determined by in vivo assays with Japanese medaka (Oryzias latipes). Environmental Toxicology and Chemistry 20 (2): 297-308 Molander L, Agerstrand M, Ruden C.

WikiPharma - a freely available, easily accessible, interactive and comprehensive database for environmental effect data for pharmaceuticals. Regulatory Toxicology and Pharmacology, 55: 367-371 Nentwig G. Effects of pharmaceuticals on aquatic invertebrates. Archives of Environmental Contamination and Toxicology 52: 163-170 Tyler CR, van Aerle R, Nilsen MV, Blackwell R, Maddix 3.58 n online pharmacy phentermine S, Nilsen BM, Berg K, Hutchinson TH, Goks0yr A. Monoclonal antibody enzyme-linked immunosorbent assay to quantify vitellogenin for studies on environmental estrogens in the rainbow trout (Oncorhynchus mykiss).



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